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In the pituitary gland, oxytocin is packaged in large, dense-core vesicles, where it is bound to neurophysin I as shown in the inset of the figure; neurophysin is a large peptide fragment of the larger precursor protein molecule from which oxytocin...
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Non-neural sources[ edit ] Endogenous oxytocin concentrations in the brain have been found to be as much as fold higher than peripheral levels. Male[ edit ] The Leydig cells in some species have been shown to possess the biosynthetic machinery to...
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At least two uncontrolled studies have found increases in plasma oxytocin at orgasm — in both men and women. This study found genital tract stimulation resulted in increased oxytocin immediately after orgasm. In contrast, vasopressin was increased during arousal but returned to baseline at the time of ejaculation. The study concludes that in males vasopressin is secreted during arousal, while oxytocin is only secreted after ejaculation.
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The authors noted these changes "may simply reflect contractile properties on reproductive tissue". In several species, oxytocin can stimulate sodium excretion from the kidneys natriuresis , and, in humans, high doses can result in low sodium levels hyponatremia. Cardiac effects: oxytocin and oxytocin receptors are also found in the heart in some rodents, and the hormone may play a role in the embryonal development of the heart by promoting cardiomyocyte differentiation.
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This silences the fetal brain for the period of delivery and reduces its vulnerability to hypoxic damage. This population of oxytocin neurons is absent in Prader-Willi syndrome , a genetic disorder that leads to uncontrollable feeding and obesity, and may play a key role in its pathophysiology. Vasopressin appears to have a similar effect in males. In a study, both humans and dog oxytocin levels in the blood rose after five to 24 minutes of a petting session. This possibly plays a role in the emotional bonding between humans and dogs. Race can be used as an example of in-group and out-group tendencies because society often categorizes individuals into groups based on race Caucasian, African American, Latino, etc.
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UNIT 5: PROTEIN SYNTHESIS
One study that examined race and empathy found that participants receiving nasally administered oxytocin had stronger reactions to pictures of in-group members making pained faces than to pictures of out-group members with the same expression. Oxytocin has also been implicated in lying when lying would prove beneficial to other in-group members. In a study where such a relationship was examined, it was found that when individuals were administered oxytocin, rates of dishonesty in the participants' responses increased for their in-group members when a beneficial outcome for their group was expected. Oxytocin is not only correlated with the preferences of individuals to associate with members of their own group, but it is also evident during conflicts between members of different groups.
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During conflict, individuals receiving nasally administered oxytocin demonstrate more frequent defense-motivated responses toward in-group members than out-group members. Further, oxytocin was correlated with participant desire to protect vulnerable in-group members, despite that individual's attachment to the conflict. Further, oxytocin influences the responses of individuals in a particular group to those of another group. The in-group bias is evident in smaller groups; however, it can also be extended to groups as large as one's entire country leading toward a tendency of strong national zeal. A study done in the Netherlands showed that oxytocin increased the in-group favoritism of their nation while decreasing acceptance of members of other ethnicities and foreigners. Thus, oxytocin appears to affect individuals at an international level where the in-group becomes a specific "home" country and the out-group grows to include all other countries. Drugs[ edit ] Drug interaction : According to several studies in animals, oxytocin inhibits the development of tolerance to various addictive drugs opiates , cocaine , alcohol , and reduces withdrawal symptoms.
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The status of the endogenous oxytocin system can enhance or reduce susceptibility to addiction through its bidirectional interaction with numerous systems, including the dopamine system, the hypothalamic—pituitary—adrenal axis and the immune system. Individual differences in the endogenous oxytocin system based on genetic predisposition, gender and environmental influences, may therefore affect addiction vulnerability. Fear and anxiety[ edit ] Oxytocin is typically remembered for the effect it has on prosocial behaviors , such as its role in facilitating trust and attachment between individuals.
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There is consensus that oxytocin modulates fear and anxiety ; that is, it does not directly elicit fear or anxiety. Thus, oxytocin increases the salience of cues that imply contamination, which leads to a faster response because these cues are especially relevant for survival. In another study, after administration of oxytocin, individuals displayed an enhanced ability to recognize expressions of fear compared to the individuals who received the placebo. Rats that are genetically modified to have a surplus of oxytocin receptors display a greater fear response to a previously conditioned stressor. Oxytocin enhances the aversive social memory, leading the rat to display a greater fear response when the aversive stimulus is encountered again.
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Crystal structure of dry ice Carbon dioxide was the first gas to be described as a discrete substance. In about , [21] the Flemish chemist Jan Baptist van Helmont observed that when he burned charcoal in a closed vessel, the mass of the resulting ash was much less than that of the original charcoal. His interpretation was that the rest of the charcoal had been transmuted into an invisible substance he termed a "gas" or "wild spirit" spiritus sylvestris. He found that limestone calcium carbonate could be heated or treated with acids to yield a gas he called "fixed air. Black also found that when bubbled through limewater a saturated aqueous solution of calcium hydroxide , it would precipitate calcium carbonate. He used this phenomenon to illustrate that carbon dioxide is produced by animal respiration and microbial fermentation.
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In , English chemist Joseph Priestley published a paper entitled Impregnating Water with Fixed Air in which he described a process of dripping sulfuric acid or oil of vitriol as Priestley knew it on chalk in order to produce carbon dioxide, and forcing the gas to dissolve by agitating a bowl of water in contact with the gas.
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The carbon—oxygen bond length is Stretching and bending oscillations of the CO2 carbon dioxide molecule. Upper left: symmetric stretching. Upper right: antisymmetric stretching. Lower line: degenerate pair of bending modes. As a linear triatomic molecule, CO2 has four vibrational modes as shown in the diagram. However, the symmetric stretching mode does not create a dipole and so is not observed in the IR spectrum. The two bending modes are degenerate, meaning that they correspond to only one frequency. It has been shown both by theory [29] and by Coulomb explosion imaging experiments [30] that this is never actually true for both modes at once. In a gas phase sample of carbon dioxide, none of the molecules are linear as a result of the vibrational motions. However, the molecular geometry is still described as linear, which describes the average atomic positions corresponding to minimum potential energy. In aqueous solution Carbon dioxide is soluble in water, in which it reversibly forms H 2CO 3 carbonic acid , which is a weak acid since its ionization in water is incomplete.
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Unit 5 Test Review Biology Answer Key
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